Mutations causing Bloom syndrome have been identified in two new genes by an international collaboration of scientists including also researchers of the Institute of Human Genetics Göttingen. [...]
Protein-bound iron-sulphur clusters are important biological cofactors and play a crucial role in electron transfer reactions. Additionally, they fulfill essential functions in diverse cellular [...]
Genetic or functional dependencies are often used by cancer cells to compensate the loss of function of one gene by the function of another gene in order to persist. By using genome-wide analyses [...]
The proteasome is a complex machinery in each cell which unfolds and breaks down proteins that are misfolded, damaged or no longer needed. The proteasome maturation protein (POMP) is essential [...]
Scientists from Norway and Switzerland uncovered for the first time a mutation in EPO, the gene encoding erythropoetin, as the genetic cause of an autosomal dominantly inherited form of [...]
During translation, a number of obstacles have the potential to arrest the ribosomal movement. In yeast, several studies revealed that the evolutionarily conserved Pelota (Pelo) recognizes [...]
An important role of the EDC4 gene in the intricate network regulating the repair of DNA damage and in cancer development has now been uncovered. In a study recently published in Nature [...]
Transforming growth factors beta (TGF-β) are vital in embryonic development and the regulation of many fundamental cellular functions in the human body. By binding and activating specific [...]
The 11th Molecular Biology of Hearing and Deafness Conference will be held from May 16th to 19th, 2018, at the Max Planck Institute of Biophysical Chemistry in Göttingen. This international [...]
