Gene of the Month

Gene of the Month – July: ARAF

A mutation in ARAF was discovered by US researchers as the genetic cause of a very rare and complex lymphatic anomaly and then served as the basis for developing a therapeutic approach. In Nature [...]

Gene of the Month – June: RFC1

Replication factor C subunit 1, the protein encoded by the RFC1 gene, is the largest of five subunits making up the RFC protein complex. This complex loads the ring-shaped PCNA protein onto the [...]

Gene of the Month – May: RRAS2

The protein encoded by RRAS2 is a ubiquitously expressed small GTPase with an important function as a signal transducer in the cell. Disturbances in signaling cascades controlling the cell’s [...]

Gene of the Month – April: MC4R

The melanocortin-4 receptor (MC4R) belongs to the family of G protein-coupled receptors, which play essential roles in signal processing and transduction in our cells. MC4R is expressed primarily [...]

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