CDK10 mutations cause new syndrome of growth retardation, facial dysmorphism, developmental delay and spine malformations

Autosomal recessive mutations of the CDK10 gene have been revealed as causing a newly described syndrome characterized by a combination of severe growth retardation, dysmorphic facial features, [...]

Novel potential strategy to enhance the efficacy of colorectal carcinoma treatment uncovered

Researchers led by Dr Silke Kaulfuß at the Institute of Human Genetics Göttingen have uncovered a new approach that may increase the efficacy of the standard therapy to treat colorectal cancer [...]

UMG researchers are unravelling important functional aspects of “broken-heart syndrome”

It is an acute and life-threatening functional disturbance of the heart with symptoms similar to a heart attack, and it really is not so rare: Takotsubo syndrome (TTS) is also called [...]

Gene(s) of the Month – August: KEOPS complex genes OSGEP, TP53RK, TPRKB and LAGE3

The so-called KEOPS protein complex has been implicated in a range of functions. Among others, it regulates a chemical modification of tRNA which ensures accurate translation, and it also acts in [...]